Putting the below in /etc/sysctl.conf both client and server machine, helped me a whole lot. I was seeing a lot of hesitations and heavy memory *and* swap usage on the server, especially after time idle, as well as overall desktop latency and audio breakup; these knocked it all out. 2G RAM on 1GHz single-CPU old laptop client, 4G on quad-2.6GHz AMD X2 server.
net.ipv4.tcp_rfc1337=1 net.ipv4.tcp_window_scaling=1 net.ipv4.tcp_workaround_signed_windows=1 net.ipv4.tcp_sack=1 net.ipv4.tcp_fack=1 net.ipv4.tcp_low_latency=1 net.ipv4.ip_no_pmtu_disc=0 net.ipv4.tcp_mtu_probing=1 net.ipv4.tcp_frto=2 net.ipv4.tcp_frto_response=2 net.ipv4.tcp_congestion_control=illinois vm.swappiness=10
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